Thursday, April 23, 2009

Causes of Mesothelioma....


Asbestos is made up of tiny fibres that are extremely strong, but can be woven like cotton. Asbestos is highly resistant to heat and was commonly used in household items and building materials (such as interior and exterior wall sheeting and insulation). You may have had an asbestos mat that you used on your stove top to protect Pyrex coffee pots, or you may have had asbestos-lined gloves and oven mitts.

Asbestos only causes problems when it's cut or disturbed in some way because this releases the tiny fibres that you can breathe in. Once inside the lungs, these fibres can cause inflammation, fibrosis (scarring) and cancer. Asbestos can also be swallowed when the tiny fibres are air borne.

Industries at Risk

So who can get mesothelioma? 

Some cases require prolonged and high exposure levels, such as those of people who worked, unprotected, in industries using asbestos prior to 1970. These industries include:

·         factories

·         shipyards

·         mines

·         military

·         engineers

·         pipe fitters

·         steel workers

·         auto mechanics

·         construction

How Much Exposure is Dangerous?

But other patients received relatively short exposure, sometimes only months or weeks. Cases have been recorded of patients whose only exposure was when changing the brake linings on their cars and breathing the dust.

Others had "passive" exposure, such as women who washed their husbands and son's work clothes.

The disease can appear 20 years after exposure or as long as 50 years after, and some experts believe that cases will continue to rise until at least 2020.

Always seek competent medical advice so your doctor can make an accurate diagnosis. The earlier you're diagnosed, the better your chances.

Mesotherapy

Pioneered by the French physician Dr. Michel Pistor in 1952, Mesotherapy is a minimally invasive procedure that is widely used in Europe and elsewhere to treat various injuries and medical conditions. This medical specialty targets problem areas with microinjections of conventional or homeopathic medicines, vitamins, minerals and amino acids. Tiny "medicinal bullets" are delivered directly into the mesoderm (middle layer of skin) that are highly specific to the condition being treated. Among its many applications, Mesotherapy can be used for the following:
Mesotherapy to eliminate cellulite
Mesotherapy to promote weight loss
Mesotherapy to provide anti-aging benefits
Mesotherapy to eliminate localized fat deposits Mesotherapy ( Mesotherapie) was recognized by the French National Academy of Medicine in 1986 as an integral part of traditional medicine. Each day, thousands of doctors worldwide use Mesotherapy to help tens of thousands of patients.
Mesotherapy is a technique, invented in 1952 by Dr. Michel Pistor, where medication is injected into the mesoderm, the layer of fat and connective tissue under the skin. Over the past 50+ years, in excess of 30,000 physicians worldwide have used Mesotherapy regularly for a variety of purposes, including overall weight loss, spot weight reduction, cellulite reduction, hair loss, scar revision and wrinkle elimination. In 1987, the French Academy of Medicine recognized Mesotherapy as an inherent part of traditional medicine. The International Society of Mesotherapy encompasses 14 countries throughout Europe and South America. Mesotherapy is a technique using very small doses of compounded medications that are administered in specific areas, depending on the condition being treated. The medicines and plant extracts used are typically obtained from compounding pharmacies in most countries, although Europe mass manufactures many products that are prohibited for import into most other countries.
All medicines used are FDA-approved for their use. In combination, medicines for Mesotherapy are used for off-label purposes. A recent illustration of this distinction is Botox. Although Botox was FDA approved for controlling muscle spasms, the medical community embraced it for its cosmetic properties of controlling wrinkles. For many years, plastic surgeons and dermatologists used Botox for off-label purpo
Mesotherapy strengthens elastin fibres, stimulates collagen production, fights free radicals and stimulates cellular activity. Patients report Your can expect good results in your patients - loose skin to appear firmer and look younger and healthier, fine lines will be reduced and skin will “glow” as a result of Mesotherapy Treatments. Many Mesotherapists practice the specialty of Medical Aesthetics because of the beautifying effects it has on the skin. Wrinkles, cellulite and skin rejuvenation are the most effective complaints successfully treated with Mesotherapy. Mesotherapy in combination with Botox for whole face treatments are also revealing overwhelming results. The primary reason these injections are so effective for wrinkles and cellulite is that when administered correctly the injections reach not only the different layers of the skin, but the subcutaneous fat as well, helping reverse the physiology. CelluliteCellulite is a condition in which abnormal "nodules" of fat form in the midsection and thighs, more commonly in women than men. This gives the appearance of a ruffling of the skin. The condition is caused by abnormal physiology in the skin and subcutaneous fat. It involves a type of insufficiency in the venolymphatic system. Mesotherapy injections are given to not only improve the venous and lymphatic flow, but to also break down the fat nodules. The solutions generally consist of a vasodilator, lymph flow stimulator, and an anesthetic. Because cellulite involves an abnormality in fat accumulation, Mesotherapy injections should be done in conjunction with a comprehensive natural medicine program designed to improve overall metabolism. This would have the effect of increasing weight loss and improving overall health. Hormone imbalances are often at the core of the problem and need to be corrected to have maximum benefits. If the underlying physiology is corrected and maintained, then Mesotherapy is done in an initial series. If it recurs, then the process will need to be repeated. WrinklesWrinkles, like other conditions involving the skin, have a multi-factorial etiology.Excessive skin wrinkles can be caused by: overall dehydration, excessive sun exposure, genetics, facial expressions, muscle atrophy, fatty acid deficiencies, hormone imbalances, nutrient deficiencies, and many other causes. As with cellulite treatment, it is best to utilise Mesotherapy for wrinkles in the context of a comprehensive natural medicine program to correct some of the above causes. For the person with stress and increased muscle contraction in the forehead, Botox injections can be given along side the Mesotherapy treatment. MesoBotox is a the term which involves injecting multiple small doses of BOTOX into the skin of the face to reduce the action of sweat and sebaceous glands as well as the superficial layer of facial muscles which are responsible for those very fine, annoying lines of the forehead or under the eyes. The net effect is improved sheen of the face with smooth skin, tighter pores and yet the ability to move all the deeper muscles of the face thus retaining a natural, non “plastic” appearance. Patient feedback has found that MesoBotox is a welcome complement to traditional BOTOX injections.Excessive wrinkles can also be a sign of advanced or aggressive aging, which emphasizes the need even more to utilize Mesotherapy, along side of a comprehensive Mid-Life Medicine regime. This may involve the use of regenerative therapies, natural hormone replacement, nutraceuticals, appropriate metabolic-type diet, and other Mid-Life Medicine measures. As with cellulite, Mesotherapy for wrinkles may often need to be repeated after the initial series. Skin Rejuvenation - MesoliftThe aging process can be cruel to our skin - Between sun damage and progressive collagen loss, the skin loses its plumpness and resiliency. Mesotherapy skin rejuvenation or “Mesolift” infuses the dermis with potent vitamins and anti-oxidants to rejuvenate and revitalize the skin. People who have had a “Mesolift” describe their skin as firm, radiant, youthful and glowing. The "Mesolift" is usually performed in an initial series of 2-4 treatments spaced a week apart. Results are maintained by twice a year touch up sessions. Lipolysis - MesoSculpting - “The New Liposuction” Is it possible to get rid of fat without having some kind of invasive procedure?...This has long been a question pondered by many. The Mesotherapy Treatment procedure that uses Phophatydlcholine, also known as "MesoSculpting" or "Lipodissolve" is proving to answer the question with a resounding "yes".MesoSculpting for fat loss and body contouring is great news for patients who find the idea of liposuction “too much”. It is also the answer to those patients who have already had liposuction and have been left with the fat deposits around the area they had the liposuction surgery done. These fat deposits post liposuction surgery is quite common. MesoSculpting involves microinjections using various formulas. All formulas must contain Phosphatydlcholine to achieve the lipolytic effect. The injections are given directly into the areas being treated i.e. love handles, bra bulge, saddlebags, inner thighs, arms, knees, eye fat pads, double chin etc.

Monday, April 20, 2009

Asbestos 'causing teacher deaths'

Asbestos must be removed from schools to prevent the risk of cancer to pupils and teachers, a teaching union says.
228 teachers died from asbestos-related diseases between 1991 and 2005, Health and Safety Executive figures show.
The annual conference of the NASUWT teaching union agreed the government must work towards removing asbestos in all schools to halt new cancer cases.
The government says schools should know where asbestos is located and local authorities should audit schools.
Chris Keates, general secretary of the NASUWT, also criticised schools and colleges, saying some were not taking their responsibility towards staff and pupils seriously.
'Collateral damage'
Carole Hagedorn, a foreign languages teacher from Essex, told the conference about her shock at being diagnosed with mesothelioma, asbestos-related cancer.
"When, at the beginning of my career, I went into classrooms to teach Year 8s the perfect tense, I did not expect it to end with an industrial disease," she said.
She underwent 18 weeks of chemotherapy.
"I am understandably unhappy that the lack of proper asbestos control will end my life prematurely, like some sort of collateral damage or natural wastage in the education game," she said.
Hank Roberts, a teacher from Brent, accused the government of "deliberate and knowing murder" for failing to remove asbestos from schools.
He said: "If you know people will die as a result of your inaction when you could act, how is that not murder?"
He said it was "not common" for schools to clearly label where asbestos was located.
MESOTHELIOMA
A cancer of mesothelial cells which cover the outer surface of the lungs and, less commonly, the abdomen
Most cases caused by exposure to asbestos
The tiny fibres which make up asbestos are breathed in and irritate the lining of the lung, causing cell damage
"This information should be made freely available to staff - and they should know what condition the asbestos is in," he went on.
The Department for Children, Schools and Families said the health and welfare of pupils and staff was "absolutely paramount".
"By law, tough, robust processes must be in place in schools to carefully monitor asbestos, which we and the HSE continually assess.
"It is unacceptable for local authorities and school employers not to fully comply with the statutory guidance issued."
The DCSF said the Health and Safety Executive gave expert advice on asbestos control - and it advises that it is safer to carefully manage undisturbed and undamaged asbestos, rather than remove it.
The government now requires all local authorities to carry out regular surveys of the condition of school buildings, and report any asbestos.
An authority must take further action where it identifies asbestos which has been disturbed or damaged, or is likely to be and cannot be protected.
But teachers say it is not sufficient to take action only after asbestos could become harmful.
'No safe level'
The HSE - which regulates health and safety in England, Wales and Scotland - records the last known profession of every person who dies of asbestos-related cancer.
A spokesman said that the link between working in a school or college and the disease could not be established in every case, because a person could have come into contact with asbestos fibres in another location or previous profession.
He also said HSE studies had shown teachers were no more at risk than other workers.
Government advice to schools says they must:
Know if their building contains asbestos and what condition it is in
Inform anybody who may disturb the asbestos of where it is located
Refrain from pinning, stapling or tacking displays to walls and ceilings that might contain asbestos
Chris Keates, NASUWT general secretary, said: "Some schools and colleges are not taking health and safety issues like this seriously, and many local authorities are failing to comply with their statutory responsibilities.
"We welcome the fact that the Department for Children, Schools and Families is now requiring local authorities to provide information on the audits they should have conducted of asbestos in schools."
New regulations introduced by the HSE in 2006 prohibit the importation, supply and use of all forms of asbestos.
Many schools in England are now being refurbished as part of the government's Building Schools for the Future programme.
The DCSF said there were strict requirements for asbestos surveys of buildings to be carried out to identify any asbestos.
"All major refurbishments carried out under BSF would normally include removal of all asbestos," a spokesman said.
"Any asbestos that is likely to deteriorate or to be damaged or disturbed would be removed as part of the BSF programme, in line with the HSE's advice."
A Freedom of Information request recently revealed that 300 schools in Wales could also be affected by asbestos, and a recent BBC investigation revealed it was in 90% of schools in the south east of England.
MESOTHELIOMA
A cancer of mesothelial cells which cover the outer surface of the lungs and, less commonly, the abdomen
Most cases caused by exposure to asbestos
The tiny fibres which make up asbestos are breathed in and irritate the lining of the lung, causing cell damage

UK Researchers Report on Treatment for Mesothelioma



Mesothelioma Treatment, asbestos, asbestos cancer, mesothelioma

Researchers from the UK have reported on a combination treatment that could prove to be an effective treatment for sufferers of pleural mesothelioma, which is a form of cancer that is contracted through long term or higher level exposure to airborne asbestos dust and fibers.
Following testing and research the researchers have reported that a combination of Alimta® (pemetrexed) and Paraplatin® (carboplatin) could prove to be an effective treatment to help control the effects of this form of cancer in patients.
A study was carried out where this combination treatment was used on forty nine patients in the UK who were suffering from pleural mesothelioma. The drug treatment helped to improve disease control in nearly seventy percent of the patients.
Researchers also described the treatment as having been tolerated well and without having treatment related mortality. The average survival time for treatment patients was fourteen months, and the results of the study have been published in the specialist journal ‘Lung Cancer’.
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Sunday, April 12, 2009

Mesothelioma


Mesothelioma is a form of cancer that is almost always caused by exposure to asbestos. In this disease, malignant cells develop in the mesothelium, a protective lining that covers most of the body's internal organs. Its most common site is the pleura (outer lining of the lungs and internal chest wall), but it may also occur in the peritoneum (the lining of the abdominal cavity), the heart, the pericardium (a sac that surrounds the heart) or tunica vaginalis.
Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles, or they have been exposed to asbestos dust and fiber in other ways. Washing the clothes of a family member who worked with asbestos can also put a person at risk for developing mesothelioma. Unlike lung cancer, there is no association between mesothelioma and smoking, but smoking greatly increases risk of other asbestos induced cancer. Compensation via asbestos funds or lawsuits is an important issue in mesothelioma (see asbestos and the law).
The symptoms of mesothelioma include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss. The diagnosis may be suspected with chest X-ray and CT scan, and is confirmed with a biopsy (tissue sample) and microscopic examination. A thoracoscopy (inserting a tube with a camera into the chest) can be used to take biopsies. It allows the introduction of substances such as talc to obliterate the pleural space (called pleurodesis), which prevents more fluid from accumulating and pressing on the lung. Despite treatment with chemotherapy, radiation therapy or sometimes surgery, the disease carries a poor prognosis. Research about screening tests for the early detection of mesothelioma is ongoing


Signs and symptoms
Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. Shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space are often symptoms of pleural mesothelioma.
Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and pain due to ascites (a buildup of fluid in the abdominal cavity). Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.

These symptoms may be caused by mesothelioma or by other, less serious conditions.
Mesothelioma that affects the pleura can cause these signs and symptoms:
1.chest wall pain
2.pleural effusion, or fluid surrounding the lung
3.shortness of breath
4.fatigue or anemia
5.wheezing, hoarseness, or cough
6.blood in the sputum (fluid) coughed up (hemoptysis)

In severe cases, the person may have many tumor masses. The individual may develop a pneumothorax, or collapse of the lung. The disease may metastasize, or spread, to other parts of the body.
Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. 

Symptoms include:
abdominal pain
ascites, or an abnormal buildup of fluid in the abdomen
a mass in the abdomen
problems with bowel function
weight loss
In severe cases of the disease, the following signs and symptoms may be present:
blood clots in the veins, which may cause thrombophlebitis
disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs
jaundice, or yellowing of the eyes and skin
low blood sugar level
pleural effusion
pulmonary emboli, or blood clots in the arteries of the lungs
severe ascites
A mesothelioma does not usually spread to the bone, brain, or adrenal glands. Pleural tumors are usually found only on one side of the lungs.

Diagnosis

CT scan of a patient with mesothelioma, coronal section (the section follows the plane that divides the body in a front and a back half). The mesothelioma is indicated by yellow arrows, the central pleural effusion (fluid collection) is marked with a yellow star. Red numbers: (1) right lung, (2) spine, (3) left lung, (4) ribs, (5) descending part of the aorta, (6) spleen, (7) left kidney, (8) right kidney, (9) liver.
Diagnosing mesothelioma is often difficult, because the symptoms are similar to those of a number of other conditions. Diagnosis begins with a review of the patient's medical history. A history of exposure to asbestos may increase clinical suspicion for mesothelioma. A physical examination is performed, followed by chest X-ray and often lung function tests. The X-ray may reveal pleural thickening commonly seen after asbestos exposure and increases suspicion of mesothelioma. A CT (or CAT) scan or an MRI is usually performed. If a large amount of fluid is present, abnormal cells may be detected by cytology if this fluid is aspirated with a syringe. For pleural fluid this is done by a pleural tap or chest drain, in ascites with an paracentesis or ascitic drain and in a pericardial effusion with pericardiocentesis. While absence of malignant cells on cytology does not completely exclude mesothelioma, it makes it much more unlikely, especially if an alternative diagnosis can be made (e.g. tuberculosis, heart failure).
If cytology is positive or a plaque is regarded as suspicious, a biopsy is needed to confirm a diagnosis of mesothelioma. A doctor removes a sample of tissue for examination under a microscope by a pathologist. A biopsy may be done in different ways, depending on where the abnormal area is located. If the cancer is in the chest, the doctor may perform a thoracoscopy. In this procedure, the doctor makes a small cut through the chest wall and puts a thin, lighted tube called a thoracoscope into the chest between two ribs. Thoracoscopy allows the doctor to look inside the chest and obtain tissue samples.
If the cancer is in the abdomen, the doctor may perform a laparoscopy. To obtain tissue for examination, the doctor makes a small incision in the abdomen and inserts a special instrument into the abdominal cavity. If these procedures do not yield enough tissue, more extensive diagnostic surgery may be necessary.